MELANOMAX LISTER 90 capsules
€59.00
Availability:
In Stock
Recover your hair’s natural color.
Melanomax Lister +
Benefits
Helps in the recovery of natural hair color
Strengthens hair
DESCRIPTION
Melanin biosynthesis takes place in melanosomes, specialized melanocyte organelles, dendritic cells, located in the basal layer of the epidermis. L-Tyrosine and dopaquinone (derived from L-DOPA), are essential for their formation. L-Tyrosine and L-DOPA (L-dihydroxyphenylalanine) are, therefore, substrates for melanogenesis, and although they follow different metabolic pathways, they seem to be related with respect to the biochemical-physiological effects that lead to the formation of Melanin. In addition to being substrates for the formation of Melanin, L-Tyrosine and L-DOPA, act as positive inducers and regulators of melanogenic metabolic pathways, with direct or indirect interference from specific receptors and processes not mediated by receptors. The various melaninic components (eumelin and phaeomelanin) are related to the pigmentation of the hair follicle (follicular melanocytes, keratinocytes, dermal papilla fibroblasts). The capillary bulb, which contains a high amount of melanocytes, is essential for capillary pigmentation. L-Tyrosine and L-DOPA are also important in these biochemical-physiological processes (molecular physiology). The melanocytes of the black hair follicles contain the largest number of melanosomas with a high eumelanin content, which have a high electron density. The brown hair bulbs are more poorly melanized, having a preponderance of phaeomelanin, and in red hair the melanin is irregularly deposited in the form of flocculent material. With aging, melanocytes become dysfunctional and do not contain melanin, thus leading to hair whitening. Supplementation with melanin thus proves to be of enormous importance. L-Methionine is a sulfur amino acid that contributes to reversing the hair whitening process, as it prevents the oxidation of methionine itself and contributes to the formation of methionine sulfoxide reductase A and B, preventing the decrease in methionine’s biochemical functionality. sulfoxide, thus contributing to the replacement of the dark color in the grayish follicle.
At the skin level, Melanin has a protective effect against ultraviolet radiation, thus creating a darkening process (tanning). Although its biological value in terms of hair pigmentation is less evident, the research points towards Melanin fixing toxins and heavy metals in the hair, which after cutting will be eliminated quickly from the body. Differences in skin color also result from melanogenic activity, the type of Melanin produced in melanosomes and the number and size of melanosomes, which can vary between 17.9% and 72.3%. Melanin plays, as previously mentioned, a photoprotective role in relation to UV (UVR, particularly), with eumelin being an efficient captor of free radicals, reducing ROS (super-reactive oxygen species), through the induction of superoxide dismutase. Some studies point to pheomelanin as a promoter of the production of free radicals, in particular hydrogen peroxide and superoxide anions. As eumelanin is evident, it should counteract these biochemical-physiological deviations, and the use of L-Methionine as a synergist in the formulation, also plays a decisive role with regard to this activity.
The addition of standardized extract of Piper nigrum to 95% piperine, to the formulation, aims to provide an increase in the bioavailability of the other components. Studies indicate that piperine increases assimilation at the intestinal level, but also contributes to increasing the time of metabolic availability of substances administered concomitantly, evidenced by the highest serum peaks and prolonged time of physiological activity.
The Melanin contained in the formulation comes from hydrolyzed keratin, standardized to>> 0.5% of this peptide pigment and produced from black sheep’s wool. It is an innovative ingredient for use in food supplements. This ingredient, significantly promotes hair recoloring after two months of use, and increases the dark color if its use lasts for several months.
This ingredient stimulates the melanocytes of the hair bulb, in order to repigment from the base. However, it also contributes to reduce hair loss and strengthen its structure, stimulating the activity and regeneration of keratinocytes. It also protects from the oxidizing effects of free radicals. Its effects on skin metabolism are also evident, as this pigment, when exercising a protective effect in relation to ultraviolet radiation, induces tanning.
Subjective evaluation:
• 95% of satisfied subjects,
• 87% of subjects who consider their hair to be more colored,
• 84% of subjects who intend to continue using the ingredient,
• 85% would recommend the product to others.
A clinical study (nº 14 E 1495), using the Dermscan method (Dermscan group), carried out for 120 days in 32 subjects with prototype I and II that did not color their hair, using 650mg of standardized hydrolyzed keratin at>> 0, 5% of the peptide fraction of Melanin, aged between 46 and 76 years, with whitened hair and using Chromameter® technology, confirms the ability to reactivate capillary pigmentation, when using this innovative ingredient.
Riboflavin and selenium, a vitamin and an trace element, with beneficial effects on skin and hair metabolism, possessing health claims in this regard, approved by EU regulation No. 432/2012 of the Commission of 16 May 2012. Acid folic acid, prevents the increase of homocysteine with subsequent damage to deoxyribonucleic acid13, which may be particularly beneficial for the good condition of the hair, as it avoids aggressions at the level of the capillary melanocytes.
Hydrolyzed keratin
Hydrolyzed keratin is very important in the treatment of damaged hair because it increases the concentration of cystine available in the hair strands, strengthening and recovering the damage and thus increasing the tensile strength. Hydrolyzed keratin is indicated for strengthening brittle and damaged hair. Its main benefits are: it replenishes losses resulting from chemical aggressions (coloring, straightening), and physical ones (elastic, mistreatment), and natural agents (salt, sun); and strengthens the weakness of the thread.
Melanin
Melanin is a type of protein produced from tyrosine. It is responsible for coloring the skin, hair and hair, as well as protecting the cells’ DNA against the ultraviolet radiation emitted by the sun. Some foods such as carrots, tomatoes, mangoes and melons help to improve the production of melanin in our bodies.
Gelatin
Gelatin is a great source of hydration ideal for use in diets. It is a great source of collagen that helps strengthen nails and hair, giving them greater shine, thickness, growth and resistance.
In addition to these benefits, gelatin helps to combat constipation, maintain bones and restore and regenerate joints to delay the natural sagging process of aging.
L-tyrosine
L-Tyrosine is one of the 20 amino acids that are part of proteins, considered a non-essential amino acid (the body can produce it). It is recommended to aid in intensive training phases, relieve chronic muscle tension, increase personal performance, soothe headaches and migraines, treat emotional distress and insomnia, and strengthen motivation and well-being.
L-Methionine
Methionine is an essential amino acid – it is not produced by the body so it needs to be ingested through foods such as eggs, fish, chicken, cheese and milk. This amino acid offers several health benefits: it helps in liver disease and muscle pain, it fights hepatitis and cirrhosis, it helps treat urinary infections, it helps prevent chronic depression and it is essential for the production of some substances such as collagen, cysteine and taurine.
Methionine also has benefits in aesthetics because it helps in healthy hair growth as it is an amino acid necessary for the formation of the molecular chains of hair and skin. The stronger the methionine is the hair growth, also contributing to healthier and more beautiful skin, nails and hair.
Vicia Faba
Vicia Faba, better known as fava bean, is rich in iron, B vitamins, magnesium and starch, a nutrient that provides energy to the body. It also has in its composition soluble fibers that help digestion by controlling cholesterol, triglycerides and blood sugar.
Its benefits are: it fights infectious diseases, controls blood pressure, stimulates digestion, reduces irritation and stress, improves intestinal function, helps in the treatment of diabetes and stimulates growth.
Piper nigrum (black pepper)
Black pepper is widely used as a condiment and for the preservation of meat in canning industries. It contains piperine (98%), vitamin A, vitamin C, iron, potassium, flavones and flavonoids.
Its benefits are its digestive function, metabolism activation, antioxidant power, anti-inflammatory properties and increased absorption of selenium, vitamin B, C, Beta-carotene and Curcuma.
Vitamin B2
Vitamin B2 (riboflavin) is one of the water-soluble vitamins of the B complex. Its daily intake is recommended taking into account that our bod stores only small doses. This vitamin can be found in broccoli, eggs, milk, yogurt and spinach.
Vitamin B2 is converted in the body into two coenzymes: FAD and FMN, which play important roles in the metabolism of fats, proteins, drugs and steroids, in the production of energy through the respiratory chain, and in the development, growth and cellular function.
Folic acid
Folic acid, often referred to as vitamin B9, is involved in various functions in our body, mainly in the formation of DNA and the genetic content of cells. Folic acid has very important benefits for our body such as maintaining brain health, preventing anemia, cardiovascular diseases and some types of cancer. This vitamin is very important for maintaining the health of the brain, the vascular system and the immune system.
Selenium
Selenium is a micronutrient with several functions in the body and is one of the 26 essential elements for the development of living organisms. The concentration of selenium in the body is influenced by the environment and food. Skeletal muscle is the main storage site for this micronutrient and accounts for about 28-46% of the selenium in the body, and it can also be found in the liver, kidneys and heart.
This micronutrient contributes to normal spermatogenesis, maintenance of hair and nails, normal functioning of the immune system, normal thyroid function and protection of cells against undesirable oxidation.
For what?
Melanomax Lister + will strengthen your weak and brittle hair, helping you to recover from external aggressions.
For whom?
This food supplement is indicated for those who feel the need to improve the appearance of their hair.
| Ingredients | |
| Hydrolyzed keratin standardized to> >0.5% Melanin peptide fraction | 650 mg. |
| L-Tyrosine | 220 mg. |
| L-Methionine | 100 mg. |
| Vicia Faba (extract titrated to> >2.5% L-DOPA) | 80 mg. |
| Piper Nigrum | 5 mg. |
| Vitamin B2 | 2,8 mg. |
| Folic acid | 600 μg |
| Selenium | 110 μg |
INGREDIENTS
Hydrolyzed keratin standardized to>> 0.5% Melanin peptide fraction; Gelatine; L-Tyrosine; L-Methionine; Vicia Faba (extract titrated to>> 2.5% L-DOPA); Piper Nigrum; Vitamin B2 (riboflavin); Folic Acid (folate); Selenium (selenomethionine).
PRESENTATION
Bottle with 90 capsules.
HOW TO TAKE
2 capsules 5 to 10 minutes before breakfast and 1 capsule 5 to 10 minutes before dinner.
Do not exceed the recommended dosages.
CONTRAINDICATIONS
It should not be used by pregnant or lactating women, nor in case of hypersensitivity or allergy to any of the constituents of the formulation.
Scientific references:
- 1 From tyrosine to melanin: Signaling pathways and factors regulating melanogenesis. Rzepka Z, Buszman E, Beberok A, Wrzesniok D. Postepy Hig Med Dosw (online). 2016 Jun 30; 70 (0): 695-708.
- 2 Positive regulation of melanin pigmentation by two key substrates of melanogenic pathway, L-tyrosine and L-dopa. Slominski A, Moellmann G, Kuklinska E, Bomirski A, Pawelek J. J Cell Sci. 1988 Mar; 89 (Pt 3): 287-96.
- 3 L-tyrosine and L-dopa as hormone-like regulators of melanocytes functions. Slominski A, Zmijewski M, Pawelek J. Pigment Cell Melanoma Res. 2012 Jan; 25 (1): 14-27.
- 4 Hair follicle pigmentation. Slominski A, Wortsman J, Przmyslaw MP, Paus R, Shallreuter KU, Tobin DJ. J Inves Dermatol. 2005 Jan; 124 (1): 13-21.
- 5 Oxidative stress in aging of hair. Trüeb RM. Int J Trichology. 2009 Jan-Jun; 1 (1): 6-14.
- 6 Senile hair graying: H202- mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair. Wood JM, Decker H, Hartmann H, Chavan B, Rokos H, Spencer JD, Hasse S, Thornton MJ, Shalbaf M, Paus R, Shallreuter KU. FASEB J. 2009 Jul; 23 (7): 2065-75.
- 7 The redox-biochemistry of human hair pigmentation. Shallreuter KU, Salem MM, Hasse S, Rokos H. Pigment Cell Melanoma Res. 2011 Feb; 24 (1): 51-62.
- 8 Graying: gerontobiology of the hair follicle pigmentary unit. Tobin DJ, Paus R. Exp Gerontol. 2001 Jan; 36 (1): 29-54.
- 9 Human hair pigmentation- Biological aspects. Tobin DJ. Int J Cosmet Sci. 2008 Aug; 30 (4): 233-57.
- 10 The protective role of melanin against UV damage in human skin. Brenner M, Hearing VJ. Photochem Photobiol. 2008; 84 (3): 539-549.
- 11 Bioavailability enhancers of herbal origin: an overview. Kesarrwani K, Gupta R. Asian Pacific Journal of Tropical Biomedicine. 2013 Apr; 3 (4): 253-66.
- 12 Influence of Piperine on the pharmacokinetics of Curcumin in animals and human volunteers. Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Planta Med. 1998 May; 64 (4): 353-6.
- 13 Folate deficiency and plasma homocysteine during increased oxidative stress. Rogers EJ, Chen S, Chan A. N Engl J Med. 2007 Jul 26; 357 (4): 421-2
| Weight | 0.1 g |
|---|
You may also like…
Reviews
There are no reviews yet.